The World Health Organization authorized a second malaria vaccine on Monday, a decision that could offer countries a cheaper and a more readily available option than the against the parasitic disease.
WHO Director-General Tedros Adhanom Ghebreyesus said the U.N. health agency was approving the new malaria vaccine based on the advice of two expert groups, recommending its use in children at risk of the disease.
香蕉视频直播淎s a malaria researcher, I used to dream of the day we would have a safe and effective vaccine against malaria. Now we have two,香蕉视频直播 Tedros said.
Oxford University developed the new three-dose vaccine with help from the Serum Institute of India. Research suggests it is more than 75% effective and that protection is maintained for at least another year with a booster. Tedros said the shot would cost about $2 to $4 and could be available in some countries next year if funders agree to buy it.
Earlier this year, regulatory authorities in Ghana and Burkina Faso approved the vaccine.
香蕉视频直播淭his is one more tool we will now have, but it香蕉视频直播檚 not going to replace bed nets and spraying insecticides,香蕉视频直播 said John Johnson with Doctors Without Borders. 香蕉视频直播淭his is not the vaccine that香蕉视频直播檚 going to stop malaria.香蕉视频直播
Johnson was not part of the WHO expert group that gave the Oxford vaccine the green light.
In 2021, WHO endorsed the first malaria vaccine in what it described as a 香蕉视频直播渉istoric香蕉视频直播 effort to end the devastating toll the mosquito-transmitted disease has on Africa, home to most of the world香蕉视频直播檚 estimated 200 million cases and 400,000 deaths.
But that vaccine, known as Mosquirix and made by GSK, is only about 30% effective, requires four doses and protection fades within months. WHO experts, however, said the data to date on the GSK and Oxford-developed vaccines does not show which one is more effective.
The Bill & Melinda Gates Foundation, one of the GSK vaccine香蕉视频直播檚 biggest backers, Mosquirix directly in 2015, saying it was less effective than officials would like and that funding would be better used elsewhere. The foundation said it has continued helping with the vaccine rollout by supporting Gavi, a global vaccines alliance that is buying the GSK shots for distribution in poorer countries.
香蕉视频直播淭he big difference with these two vaccines is access,香蕉视频直播 Johnson said, noting that only about a dozen countries are scheduled to get limited quantities of the GSK vaccine in the next few years.
GSK has said it can only produce about 15 million doses a year. The Serum Institute has said it could make up to 200 million doses of the Oxford vaccine a year.
Alister Craig, an emeritus professor at the Liverpool School of Tropical Medicine, said he would recommend countries trying to get the GSK vaccine switch to the Oxford vaccine instead.
If the new vaccine is rolled out widely across Africa, it could dramatically reduce the amount of severe illness and deaths caused by malaria in a few years, Craig said.
Neither of the malaria vaccines stop transmission so immunization campaigns alone won香蕉视频直播檛 be enough to stop epidemics. Efforts to curb the disease are also being complicated by increasing reports of resistance to the main drugs used to treat malaria and the spread of .
香蕉视频直播淵ou would be foolish to think that this vaccine is going to be the end of the malaria story,香蕉视频直播 Craig said.
In a separate decision, WHO香蕉视频直播檚 expert group also authorized the dengue vaccine made by Takeda, which was previously approved by the European Union drug regulator.
There is no specific treatment for dengue, common in tropical Latin American and Asian countries. While most infections are mild, severe cases of the mosquito-spread disease can lead to internal bleeding, organ damage and death.
WHO香蕉视频直播檚 expert groups advised that the Takeda dengue vaccine be used in children aged 6 to 16 in countries with a high prevalence of the disease.
Previous studies have showed Takeda香蕉视频直播檚 vaccine was about 84% effective in preventing people from being hospitalized with dengue and about 61% effective in stopping symptoms four years after getting immunized.
Nearly 1,000 people have been killed by dengue this year in an ongoing epidemic in Bangladesh, the country香蕉视频直播檚 worst outbreak of the disease.
Maria Cheng, The Associated Press